Max Planck Institute of Biophysics

Geschichte

The Max Planck Institute of Biophysics is located in Frankfurt am Main, Germany. It was founded as Kaiser Wilhelm Institute for Biophysics in 1937, and moved into a new building in 2003. It is one of 80 institutes in the Max Planck Society .A prerequisite for the understanding of the fundamental processes of life is the knowledge of the structure of the participating macromolecules. Two of the four departments are devoted to the challenging task of determining the structure of membrane proteins. Under the direction of Hartmut Michel, the Department of Molecular Membrane Biology approaches this problem primarily by x-ray crystallography, whereas the Department of Structural Biology, headed by Werner Kühlbrandt, uses the complementary technique of electron microscopy. The Department of Biophysical Chemistry, directed by Ernst Bamberg, studies the function of these proteins in native or reconstituted membranes by electrophysiological and spectroscopic methods. The fourth department "Molecular Neurogenetics" under the direction of Peter Mombaerts has started its work in 2007. Since 2013, the institute hosts a new department "Theoretical Biophysics", directed by Gerhard Hummer focusing on development and implementation of broad range of computational and theoretical methods to bridge fundamental physics, chemistry and biology of molecular systems.

"Am Max-Planck-Institut für Biophysik untersuchen wir hauptsächlich Protein-Bausteine, die in der Zellhülle, der Membran, sitzen. Diese Membranproteine ermöglichen es der Zelle, Nährstoffe und Informationen mit Ihrer Umgebung auszutauschen. Ihre Erforschung liefert uns daher wichtige Erkenntnisse über die Entstehung von Erkrankungen und für die Entwicklung neuer Arzneistoffe.The Max Planck Institute of Biophysics focuses on investigating the structure and function of proteins that are embedded in cellular membranes. Membrane proteins functioning as channels, transporters, or molecular sensors mediate the exchange of matter and information between cells and their environment."